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Your Position: Home > Cytokines-old > CCL17 > CC7-H5256

Human CCL17 / TARC Protein, Fc Tag (MALS verified)

  • Synonym
    TARC/ABCD-2/SCYA17/A-152E5.3
  • Source
    Human CCL17, Fc Tag (CC7-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 94 (Accession # Q92583-1).
    Predicted N-terminus: Ala 24
  • Molecular Characterization
    Online(Ala 24 - Ser 94) Q92583-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 34.5 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100mM Gly, 25mM Arginine, 150mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CCL17, Fc Tag (Cat. No. CC7-H5256) SDS-PAGE gel

Human CCL17, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human CCL17, Fc Tag (Cat. No. ) MALS images

The purity of Human CCL17, Fc Tag (Cat. No. CC7-H5256) is more than 95% and the molecular weight of this protein is around 80-108 kDa verified by SEC-MALS.

  • Background
    This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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