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Your Position: Home > Others > CR2 > CD2-H52H4

Human Complement Receptor type 2 Protein, His Tag (MALS verified)

  • Synonym
    CD21
  • Source
    Human Complement Receptor type 2 Protein, His Tag (CD2-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Arg 971 (Accession # P20023-1).
    Predicted N-terminus: Ile 21
  • Molecular Characterization
    Online(Ile 21 - Arg 971) P20023-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 106.1 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Complement Receptor type 2 Protein, His Tag (Cat. No. CD2-H52H4) SDS-PAGE gel

Human Complement Receptor type 2 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human Complement Receptor type 2 Protein, His Tag (Cat. No. ) MALS images

The purity of Human Complement Receptor type 2 Protein, His Tag (Cat. No. CD2-H52H4) is more than 85% and the molecular weight of this protein is around 120-140 kDa verified by SEC-MALS.

  • Background
    Epstein-Barr virus (EBV), also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV binds to the cell surface receptor 2 (CD21/CR2) on human B cells using its major envelope glycoprotein 350 (gp350) and, as such, the EBV gp350 Envelope Protein, also designated the EBV envelope glycoprotein complex 250/350, is crucial in mediating the initial stages of EBV infection. The EBV gp350 Envelope Protein is expressed on virion envelope as well as EBV producer cells.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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