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Your Position: Home > Protein > CLEC-2 > CL2-H5247

Human CLEC-2 / CLEC1B Protein, His Tag (MALS verified)

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  • Synonym
    CLEC-2,CLEC1B,C-type Lectin-like Receptor 2
  • Source
    Human CLEC-2, His Tag(CL2-H5247) is expressed from human 293 cells (HEK293). It contains AA Ser 55 - Pro 229 (Accession # Q9P126-1).
    Predicted N-terminus: His
  • Molecular Characterization
    CLEC-2 Structure

    This protein carries a polyhistidine tag at the N-terminus

    The protein has a calculated MW of 22.6 kDa. The protein migrates as 34-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.

Human CLEC-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

CLEC-2 MALS images

The purity of Human CLEC-2, His Tag (Cat. No. CL2-H5247) is more than 90% and the molecular weight of this protein is around 28-42 kDa verified by SEC-MALS.


Immobilized Human CLEC-2, His Tag (Cat. No. CL2-H5247) at 5 μg/mL (100 μL/well) can bind Human Podoplanin, Fc Tag (Cat. No. PON-H5254) with a linear range of 0.3-20 ng/mL (QC tested).

  • Background
    C-type lectin-like receptor 2 (CLEC-2) is a hemITAM containing receptor that is highly expressed on platelets and regulates many of the non-classical functions of these cells, including in inflammation and infection.
  • Clinical and Translational Updates

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