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Your Position: Home > Aneuro > Tau > TAU-H5144

Human Tau-441 / 2N4R (P301L) Protein, His Tag

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
  • Source
    Human Tau-441 (P301L), His Tag (TAU-H5144) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8(P301L)).
    Predicted N-terminus: Met
  • Molecular Characterization
    Online-Res(Met 1 - Leu 441) P10636-8 (P301L)

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 47.8 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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