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Your Position: Home > Aneuro > Tau > TAU-H5115

Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free

This product is still under development. Please contact us if you have interest in this product. We will accelerate the development process accordingly and reserve this product for you as request.
  • Synonym
    DDPAC,FTDP-17,MAPT,MSTD,MTBT1,Tau,PHF-tau,TAU
  • Source
    Human Tau-441 Pre-formed Fibrils, Tag Free(TAU-H5115) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8 ).
    Predicted N-terminus: Met 1
  • Molecular Characterization
    Tau Structure

    This protein carries no "tag"

    The protein has a calculated MW of 45.8 kDa.

  • Shipping

    This product is supplied and shipped as sterile liquid solution with dry ice, please inquire the shipping cost.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimers disease, frontotemporal dementia, and other tauopathies.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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