HRP conjugated Anti-Human-IgG-Fc Antibody (6F11C8), mAb

Source

HRP conjugated Anti-Human-IgG-Fc Antibody (6F11C8), mAb is a mouse monoclonal antibody derived from hybridoma cells fused with SP2/0 myeloma cells and murine B lymphocytes.

Antibody Type

Hybridoma Monoclonal

Clone

6F11C8

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Immunogen

Human-IgG-Fc

Conjugate

HRP Labeled

Specificity

This product can react with the Fc portion of Human IgG1/ IgG2/ IgG3/ IgG4 and multiple engineered variants, including: Human IgG1 (N297A), Human IgG1 (L234A/L235A), Human IgG1 (M252Y/S254T/T256E), Human IgG1 (L234F/L235E/P331S), Human IgG1 (S239D/I332E), Human IgG1 (S298A/E333A/K334A), Human IgG1 (T307A/E380A/N434A), Human IgG2 (A330S/P331S), Human IgG2 (P331S), Human IgG4 (S108P), and Human IgG4 (S228P/L235E).

Application

Cross Verification

This antibody recognizes all four human IgG isotypes (IgG1, IgG2, IgG3, and IgG4) and multiple engineered variants, including: Human IgG1 (N297A), Human IgG1 (L234A/L235A), Human IgG1 (M252Y/S254T/T256E), Human IgG1 (L234F/L235E/P331S), Human IgG1 (S239D/I332E), Human IgG1 (S298A/E333A/K334A), Human IgG1 (T307A/E380A/N434A), Human IgG2 (A330S/P331S), Human IgG2 (P331S), Human IgG4 (S108P), and Human IgG4 (S228P/L235E).
Weak cross-reactivity with cynomolgus IgG was observed by ELISA, whereas no reactivity to mouse IgG isotypes (IgG1, IgG2a, IgG2b) was detected.

Purification

Protein A purified / Protein G purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 6 months after reconstitution;
3. 2-8°C for 2-3 weeks under sterile conditions after reconstitution.

Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process