Human LYPD1 / PHTS protein, Fc Tag (MALS verified)

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Cat. No. / Size
Price
Qty
LY1-H5254-100ug
$390.00
LY1-H5254-1mg (250ug X 4)
$2885.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    LYPD1, Ly6/PLAUR domain-containing protein 1, FLJ41033, LY6/PLAUR domain containing 1, LYPDC1, PHTS, Putative HeLa tumor suppressor

  • Source

    Human LYPD1, Fc Tag (LY1-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 21 - Gly 115 (Accession # Q8N2G4-1).

    Predicted N-terminus: Leu 21

    Request for sequence
  • Molecular Characterization

    LYPD1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 36.8 kDa. The protein migrates as 43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 0.1 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    LYPD1 SDS-PAGE

    Human LYPD1, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    LYPD1 SEC-MALS

    The purity of Human LYPD1, Fc Tag (Cat. No. LY1-H5254) is more than 85% and the molecular weight of this protein is around 142-172 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     LYPD1 ELISA

    Immobilized Human LYPD1, Fc Tag (Cat. No. LY1-H5254) at 1 μg/mL (100 μL/well) can bind Anti-LYPD1 antibody with a linear range of 0.02-0.625 μg/mL (QC tested).

    Protocol

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Background

Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.

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