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Your Position: Home > CAR-T > TRDC > TRC-H52H4

Human TRDC Protein, His Tag

  • Synonym
    TRDC
  • Source
    Human TRDC, His Tag(TRC-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ser 1 - Val 129 (Accession # B7Z8K6-1 ).
  • Molecular Characterization
    TRDC Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 16.4 kDa. The protein migrates as 27-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
TRDC SDS-PAGE

Human TRDC, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    The transmembrane protein, TCR, comprise of two disulphide-linked polypeptide chains: a α and β chain, a γ and δ chain. Each polypeptide chain consists of a variable and a constant region. TRDC is the constant region of T-cell receptor (TCR) delta chain. It recognizes the non-peptide antigens frequently expressed at the epithelial boundaries, which means the antigens activating γδ T cells are mostly MHC independent. A wide range of γδ T cell functions have been described in humans and mice, including skin and mucosal epithelial wound repair, induction of tolerance, cytotoxicity and the production of various cytokines that regulate immune responses.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $2310.00

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Datasheet & Documentation

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DMF (Drug Master File)

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