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Your Position: Home > Protein > Follistatin-like 1 > FS1-H82E3

Biotinylated Human Follistatin-like 1 / FSTL1 Protein, His,Avitag™ (MALS verified)

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  • Synonym
    FSTL1,FRP,FSL1
  • Source
    Biotinylated Human Follistatin-like 1 Protein, His,Avitag(FS1-H82E3) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Ile 308 (Accession # AAH00055).
    Predicted N-terminus: Glu 21
  • Molecular Characterization
    Follistatin-like 1 Structure

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 35 kDa.

  • Labeling
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
  • Protein Ratio
    Passed as determined by the HABA assay / binding ELISA.
  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Follistatin-like 1 SDS-PAGE

Biotinylated Human Follistatin-like 1 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
Follistatin-like 1 MALS images

The purity of Biotinylated Human Follistatin-like 1 Protein, His,Avitag (Cat. No. FS1-H82E3) is more than 85% and the molecular weight of this protein is around 45-55 kDa verified by SEC-MALS.

  • Background
    Follistatin-related protein 1 (FSTL1) is also known as Follistatin-like protein 1 (FRP). FSTL1 is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain and one VWFC domain. FSTL1 is overexpressed in synovial tissues from rheumatoid arthritis. Follistatin-like protein 1 / FSTL1 may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 binds heparin.
  • Clinical and Translational Updates

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