Biotinylated Human CDCP1 Protein, His,Avitag™ (MALS verified)

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Cat. No. / Size
Price
Qty
CD1-H82E4-25ug
$360.00
CD1-H82E4-200ug
$1420.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    CUB domain-containing protein 1, CDCP1, CD318, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, TRASK, UNQ2486, PRO5773

  • Source

    Biotinylated Human CDCP1 Protein, His,Avitag (CD1-H82E4) is expressed from human 293 cells (HEK293). It contains AA Phe 30 - Thr 667 (Accession # Q9H5V8-1).

    Predicted N-terminus: Phe 30

    Request for sequence
  • Molecular Characterization

    CDCP1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 75.4 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CDCP1 SDS-PAGE

    Biotinylated Human CDCP1 Protein, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    CDCP1 SEC-MALS

    The purity of Biotinylated Human CDCP1 Protein, His,Avitag (Cat. No. CD1-H82E4) is more than 85% and the molecular weight of this protein is around 90-110 kDa verified by SEC-MALS.

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Background

CUB domain-containing protein 1, also know as CDCP1. CDCP1 is a cell surface glycoprotein that has been recognized both as a tumour marker and as a potential target to disrupt progression of cancer. CDCP1 has been shown to modulate cellsubstratum adhesion and motility in colon cancer cell lines.

Recent Advances

 
Drug Development Progress
  • English Name:

    CUB domain-containing protein 1

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

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  • Highest Development Stage:

    Preclinical

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