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Your Position: Home > Protein > Glycoprotein C (HSV-2) > GLC-V52H3

HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (MALS verified)

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  • Synonym
    Glycoprotein C (HSV-2)
  • Source
    HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag(GLC-V52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 102 - Glu 446 (Accession # P06475).
    Predicted N-terminus: Leu 102
  • Molecular Characterization
    Glycoprotein C (HSV-2) Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 39.8 kDa. The protein migrates as 52-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Glycoprotein C (HSV-2) SDS-PAGE

HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

Glycoprotein C (HSV-2) MALS images

The purity of HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (Cat. No. GLC-V52H3) is more than 90% and the molecular weight of this protein is around 45-60 kDa verified by SEC-MALS.

 Glycoprotein C (HSV-2) ELISA

Immobilized HSV-2 (strain 333) Envelope Glycoprotein C (gC), His Tag (Cat. No. GLC-V52H3) at 5 μg/mL (100 μL/well) can bind Anti-HSV2 gC antibody with a linear range of 0.6-78 ng/mL (QC tested).

  • Background
    Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein C (gC) is a structural component of the herpes simplex virus type 2 (HSV-2) envelope that mediates binding of the virus to cell surface heparan sulfate or chondroitin sulfate. Also plays a role in host immune evasion by inhibiting the host complement cascade activation (By similarity).
  • Clinical and Translational Updates

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ETD of in-stock products: 2 business days

Price(USD) : $380.00

Price(USD) : $2540.00

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