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Product Details
Synonyms
MMR, CD206, hMR, MRC1, CLEC13D, CLEC13DL, MRC1L1
Source
Biotinylated Human CD206 Protein, His Tag, primary amine labeling (CD6-H82H6) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Ala 1389 (Accession # P22897-1). It is the biotinylated form of Human CD206, His Tag (Cat. No. CD6-H52H9).
Predicted N-terminus: Leu 19
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 158.6 kDa. The protein migrates as 170-210 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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Performance Data
SDS-PAGE
Biotinylated Human CD206 Protein, His Tag, primary amine labeling on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
SEC-MALS
The purity of Biotinylated Human CD206 Protein, His Tag, primary amine labeling (Cat. No. CD6-H82H6) is more than 90% and the molecular weight of this protein is around 180-210 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Mannan from Saccharomyces cerevisiae at 20 μg/mL (100 μL/well) can bind Biotinylated Human CD206 Protein, His Tag, primary amine labeling (Cat. No. CD6-H82H6) with a linear range of 0.156-2.5 μg/mL (QC tested).
Protocol
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FAQ
- product
Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?
In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.
Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.
To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.
To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.
Supporting Document
Background
Recent Advances
Drug Development Progress- English Name：
Macrophage mannose receptor 1
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
2 Details
- Highest Development Stage：
Approved
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