Alexa Fluor™ 488-Labeled Human Glypican 3 / GPC3 Protein, His TagStar Staining

Related Products: Cell line SCCHO-ATP179 and CHEK-ATP092
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GP3-HA2H5-25ug
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GP3-HA2H5
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Synonyms

GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS , SGB, SGBS, SGBS1

Source

Alexa Fluor 488-Labeled Human Glypican 3 Protein, His Tag (GP3-HA2H5) is produced via conjugation of AF488 to Human Glypican 3 Protein, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human Glypican 3 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # P51654-1).

Predicted N-terminus: Gln 25

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

Conjugate

AF488

Excitation Wavelength: 488 nm

Emission Wavelength: 517 nm

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.