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Your Position: Home > Protein > EREG > ERG-H5264

Human EREG Protein, Fc Tag

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  • Synonym
    EPR, ER, Ep
  • Source
    Human EREG Protein, Fc Tag(ERG-H5264) is expressed from human 293 cells (HEK293). It contains AA Val 63 - Leu 108 (Accession # O14944-1).
    Predicted N-terminus: Pro
  • Molecular Characterization
    EREG Structure

    This protein carries a human IgG1 Fc tag at the N-terminus

    The protein has a calculated MW of 31.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
EREG SDS-PAGE

Human EREG Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    EREG is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4), which stimulates tyrosine phosphorylation of EGFR and ERBB4. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, EREG may promote the progression of cancers of various human tissue.
  • Clinical and Translational Updates

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Price(USD) : $350.00

Price(USD) : $2310.00

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  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 2 Clinical

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