Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (MALS verified)

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Cat. No. / Size
Price
Qty
SPN-M551-100ug
$415.00
SPN-M551-1mg (500ug X 2)
$2735.00
ETA of in-stock products:2 business days

Product Details

  • Source

    Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) is isolated from a Spike protein infected mouse and is recombinantly produced in human 293 cells (HEK293).

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    9A5E10

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Immunogen

    Recombinant SARS-CoV-2 Spike Trimer Protein (BA.4/Omicron) erived from human 293 cells

  • Specificity

    This product is a specific antibody specifically reacts with Spike protein.

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • Bioactivity-ELISA

     Spike protein ELISA

    Immobilized SARS-CoV-2 Spike Trimer, His Tag (BA.4/Omicron) (Cat. No. SPN-C5229) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (Cat. No. SPN-M551) with a linear range of 0.2-6 ng/mL (QC tested).

    Protocol
  •  Spike protein ELISA

    Immobilized SARS-CoV-2 Spike Trimer, His Tag (BA.5/Omicron) (Cat. No. SPN-C522e) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (Cat. No. SPN-M551) with a linear range of 0.2-6 ng/mL (QC tested).

    Protocol
  •  Spike protein ELISA

    Immobilized Different SARS-CoV-2 Spike protein, His Tag at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike Antibody, Human IgG1 (9A5E10) (BA.4&BA.5/Omicron Specific) (Cat. No. SPN-M551) with a linear range of 0.1-13 ng/mL (Routinely tested).

    Protocol

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Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Recent Advances

 
Drug Development Progress
  • English Name:

    Coronavirus spike glycoprotein

  • Category:

  • Approved Drugs:

    15 Details

  • Drugs in Clinical Trials:

    88 Details

  • Highest Development Stage:

    Approved

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