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Your Position: Home > Protein > SEZ6 > SE6-H52F3

Human SEZ6 Protein, Mouse IgG1 Fc Tag (HPLC verified)

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  • Synonym
    BSRPC
  • Source
    Human SEZ6 Protein, Mouse IgG1 Fc Tag(SE6-H52F3) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - His 925 (Accession # Q53EL9-1).
    Predicted N-terminus: Leu 20
  • Molecular Characterization
    SEZ6 Structure

    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 149 kDa. The protein migrates as 200-235 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-HPLC.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50mM Tris,100 mM Glycine,25 mM Argine,150 mM NaCl, PH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
SEZ6 SDS-PAGE

Human SEZ6 Protein, Mouse IgG1 Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-HPLC
SEZ6 SEC-HPLC

The purity of Human SEZ6 Protein, Mouse IgG1 Fc Tag (Cat. No. SE6-H52F3) was greater than 90% as determined by SEC-HPLC.

Bioactivity-ELISA
 SEZ6 ELISA

Immobilized Human SEZ6 Protein, Mouse IgG1 Fc Tag (Cat. No. SE6-H52F3) at 1 μg/mL (100 μL/well) can bind anti-SEZ6 antibody with a linear range of 0.1-1 ng/mL (QC tested).

  • Background
    May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity.
  • Clinical and Translational Updates

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 1 Clinical

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