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Your Position: Home > Protein > CA125 > CA5-M52H6

Mouse CA125 / MUC16 Protein, His Tag (MALS verified)

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  • Synonym
    CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16
  • Source
    Mouse CA125 Protein, His Tag(CA5-M52H6) is expressed from human 293 cells (HEK293). It contains AA Asn 7750 - Pro 8422 (Accession # A0A140LJ72-1 ).
    Predicted N-terminus: Asn 7750
  • Molecular Characterization
    CA125 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 76.7 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SEC-MALS
CA125 MALS images

The purity of Mouse CA125 Protein, His Tag (Cat. No. CA5-M52H6) is more than 90% and the molecular weight of this protein is around 120-140 kDa verified by SEC-MALS.

Bioactivity-SPR
 CA125 SPR

Biotinylated Mouse Mesothelin, His,Avitag (Cat. No. MSN-M82E7) immobilized on CM5 Chip can bind Mouse CA125 Protein, His Tag (Cat. No. CA5-M52H6) with an affinity constant of 16.4 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.
  • Clinical and Translational Updates

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ETD of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2540.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:6 Details
  • Latest Research Phase:Phase 3 Clinical

Datasheet & Documentation

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