Human MMP-10 Protein, Tag Free (Pro-form)

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Cat. No. / Size
Price
Qty
MM0-H5213-100ug
$360.00
MM0-H5213-1mg
$2680.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    SL-2, STMY2

  • Source

    Human MMP-10 Protein, Tag Free (MM0-H5213) is expressed from human 293 cells (HEK293). It contains AA Tyr 18 - Cys 476 (Accession # P09238). It needs to be activated by agents such as APMA in vitro to have hydrolytic activity.

    Predicted N-terminus: Tyr 18

    Request for sequence

  • Molecular Characterization

    MMP-10 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 52.3 kDa. The protein migrates as 44 kDa and 55-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150mM NaCl, PH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    MMP-10 SDS-PAGE

    Human MMP-10 Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity

    Measured by its ability to cleave the fluorogenic peptide substrate, Mca­-RPKPVE-­Nval­-WRK(Dnp)-NH2 .The specific activity is >450 pmol/min/µg (QC tested).

    Protocol

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Background

Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase, Similar to stromelysin 1, but action on collagen types III, IV and V is weak.

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