Product Details
Source
Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) is a chimeric monoclonal antibody recombinantly expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.
Antibody Type
Recombinant Monoclonal
Clone
1C12
Isotype
Human IgG1, Kappa
Host Species
Mouse
Reactivity
Virus
Immunogen
Recombinant Monkeypox virus (strain Zaire-96-I-16) E8 derived from human 293 cells
Specificity
This product is a specific antibody specifically reacts with E8L (MPXV).
Purification
Protein A purified / Protein G purified.
Aggregation
Less than 10%, as determined by SEC-MALS.
Concentration
Please refer to the Certificate of Analysis (CoA).
Form
Lyophilized
Formulation
Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.
Please contact us for customized product forms or formulations.
Reconstitution
Please refer to the Certificate of Analysis (CoA) for specific instructions.
Shipping
Lyophilized product is shipped at ambient temperature.
Storage
For long term storage, the product should be stored in a lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
Notices
Product Specific Notices: For research use only.
ACRO Quality Management System
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Performance Data
Bioactivity-ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) with a linear range of 0.1-2 ng/mL (QC tested).
Protocol
Bioactivity-SPR

Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) with an affinity constant of 0.119 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
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