Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Protein > Beta-NGF > BEF-M5213

Mouse Beta-NGF Protein, Tag Free (MALS verified)

Order Now

  • Synonym
  • Source
    Mouse Beta-NGF Protein, Tag Free(BEF-M5213) is expressed from human 293 cells (HEK293). It contains AA Ser 122 - Gly 241 (Accession # P01139).
    Predicted N-terminus: Ser 122
  • Molecular Characterization
    Beta-NGF Structure

    This protein carries no "tag".

    The protein has a calculated MW of 13.5 kDa. The protein migrates as <14 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 0.1 EU per μg by the LAL method.
  • Sterility
  • Mycoplasma
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 20 mM NaAC, 150 mM NaCl, pH5.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.

Mouse Beta-NGF Protein, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Beta-NGF MALS images

The purity of Mouse Beta-NGF Protein, Tag Free (Cat. No. BEF-M5213) is more than 90% and the molecular weight of this protein is around 28-36 kDa verified by SEC-MALS.


Immobilized Mouse Beta-NGF Protein, Tag Free (Cat. No. BEF-M5213) at 1 μg/mL (100 μL/well) can bind Human TrkA (33-417), Fc Tag (Cat. No. TRA-H5254) with a linear range of 0.2-16 ng/mL (QC tested).

  • Background
    Nerve growth factor beta (beta-NGF) is a neurotrophic factor that plays critical role in the development and maintenance of sensory and sympathetic neurons. The active form of human beta-NGF is is a noncovalently disulfide-linked homodimer, which is secreted and signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways.
  • Clinical and Translational Updates

Comments (0)

ETA of in-stock products: 2 business days

Price(USD) : $88.00

Price(USD) : $130.00

Price(USD) : $780.00

Promotion & Exhibitions

Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:13 Details
  • Latest Research Phase:NDA/BLA

Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Related Products

New Product Launch

Questions & Comments

This web search service is supported by Google Inc.

Call us
Call us
North America:
+1 800-810-0816 (Toll Free)
Asia & Pacific:
+86 400-682-2521
+1 888-377-6111
1 Innovation Way, Newark, DE 19711, USA

Leave a message