Product Details
Synonyms
Integrin alpha 3 beta 1, ITGA3&ITGB1
Source
Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53Wb) is expressed from CHO cells. It contains AA Phe 33 - Glu 992 & Gln 21 - Asp 729 (Accession # I4DUB5 & P49134).
Predicted N-terminus: Phe 33 & Gln 21
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA3 and ITGB1, has a calculated MW of 113.4 kDa (ITGA3) & 83.7 kDa (ITGB1). Subunit ITGA3 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The non-reducing (NR) protein migrates as 125-150 kDa (ITGA3) and 100-110 kDa (ITGB1) respectively due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
Customers Also Viewed
Performance Data
SDS-PAGE

Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free on SDS-PAGE under non-reducing (NR) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
SEC-MALS

The purity of Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-R53Wb) is more than 85% and the molecular weight of this protein is around 245-285 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Rat ITGA3 & ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-R53Wb) at 5 μg/mL (100 μL/well) can bind Human Laminin 511 Protein, premium grade (Cat. No. LA8-H5283) with a linear range of 0.1-3 ng/mL (QC tested).
Protocol
Customer Reviews Writing Reviews

Background
Recent Advances
- English Name:
Integrin alpha 3/beta 1
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
1 Details
- Highest Development Stage:
Phase 1 Clinical
[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521



















