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Your Position: Home > Antibody > PD-1 > HGS-S238

Recombinant Monoclonal Anti-PD-1 Antibody, Mouse (2F3)

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  • Background
    Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
  • Host Species

    Mouse

  • Clone

    2F3

  • Application

    IHC

  • Property
    1:500
  • State
    Liquid
  • Positive Control
    Human Tonsil Tissues
  • Clonality
    Monoclonal
  • Synonym
    PD1, CD279, PD-1, PDCD1
  • Research Field
    Cancer Drug Targets
  • Source
    Mouse
  • Isotype
    IgG
  • Storage
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Typical Data
Control Sample
 PD-1 CONTROL SAMPLE

Immunohistochemical analysis of paraffin embedded Human tonsil tissue labelled with HGS-S238 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Cancer Sample
 PD-1 CANCER SAMPLE PD-1 CANCER SAMPLE

Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S238 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

  • Clinical and Translational Updates

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Price(USD) : $122.00

Price(USD) : $491.00

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Drug Development Status

  • Number of Launched Drugs:17 Details
  • Number of Drugs in Clinical Trials:141 Details
  • Latest Research Phase:Approved

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