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Your Position: Home > Antibody > Glycoprotein D (HSV-2) > GLD-M609

Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9)

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  • Source
    Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9) is a chimeric monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Glycoprotein D (HSV-2).
  • Isotype
    Human IgG1 | Human Kappa
  • Specificity
    This product is a specific antibody specifically reacts with Glycoprotein D (HSV-2).
  • Application
    ELISA
  • Purity

    >90% as determined by SDS-PAGE.

  • Endotoxin
    Less than 1.0 EU per mg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20 to -70°C for 12 months in lyophilized state from date of receipt;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Glycoprotein D (HSV-2) SDS-PAGE

Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-Elisa
 Glycoprotein D (HSV-2) ELISA

Immobilized HSV-1 (strain 17) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9) (Cat. No. GLD-M609) with a linear range of 1-31 ng/mL (QC tested).

 Glycoprotein D (HSV-2) ELISA

Immobilized HSV-2 (strain HG52) Envelope Glycoprotein D (gD), His Tag (Cat. No. GLD-V52H4) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HSV-2-Glycoprotein D Antibody, Human IgG1 (3H9) (Cat. No. GLD-M609) with a linear range of 0.1-2 ng/mL (Routinely tested).

  • Background
    Herpesvirus infections are widely spread throughout the world population. Herpes simplex virus (HSV) belongs to the α-herpesvirus subfamily. There are two main types of HSV, HSV-1 and HSV-2, which infect humans. HSV-2 mainly causes genital lesions, whereas HSV-1 is involved in both oral and genital infections. Glycoprotein D (gD) is a structural component of the herpes simplex virus type 1 (HSV-1) envelope which is essential for virus entry and fusion with host cells. gD plays an important role by binding to the host receptors such as herpes virus entry mediator (HVEM) and nectin-1, a member of the immunoglobulin (Ig)-like cell adhesion molecules.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2310.00

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  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 2 Clinical

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