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Your Position: Home > Antibody > Hemagglutinin (HA) > HA1-M648

Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1)

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  • Source
    Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1) is a chimeric monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Hemagglutinin (HA).
  • Isotype
    Human IgG1 | Human Kappa
  • Specificity
    This product is a specific antibody specifically reacts with Hemagglutinin (HA).
  • Application
    ELISA
  • Purity

    >90% as determined by SDS-PAGE.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70 °C for 3 months after reconstitution;
SDS-PAGE
Hemagglutinin (HA) SDS-PAGE

Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-Elisa
 Hemagglutinin (HA) ELISA

Immobilized Influenza A [A/Wisconsin/588/2019 (H1N1)] HA, His Tag (Cat. No. HA1-V52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1) (Cat. No. HA1-M648) with a linear range of 0.1-1 ng/mL (QC tested).

 Hemagglutinin (HA) ELISA

Immobilized Influenza A [Wisconsin/67/2022] Hemagglutinin (HA) Protein, His Tag (Cat. No. HA1-V52H7) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1) (Cat. No. HA1-M648) with a linear range of 0.5-8 ng/mL (Routinely tested).

Bioactivity-SPR
 Hemagglutinin (HA) SPR

Monoclonal Anti-HA (A/Wisconsin/588/2019 (H1N1)) Antibody, Human IgG1 (6D1) (Cat. No. HA1-M648) captured on Protein A Chip can bind Influenza A [A/Wisconsin/588/2019 (H1N1)] HA, His Tag (Cat. No. HA1-V52H3) with an affinity constant of 0.169 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    Influenza, commonly known as 'the flu', is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle which makes it a great target for vaccine studies.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2310.00

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  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 1 Clinical

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