Human Follistatin-like 1 / FSTL1 Protein, His Tag

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Cat. No. / Size
Price
Qty
FS1-H5227-100ug
$260.00
FS1-H5227-1mg (250ug X 4)
$1700.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    FSTL1, FRP, FSL1

  • Source

    Human Follistatin-like 1, His Tag (FS1-H5227) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Ile 308 (Accession # AAH00055).

    Predicted N-terminus: Glu 21

    Request for sequence
  • Molecular Characterization

    Follistatin-like 1 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 33.8 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Follistatin-like 1 SDS-PAGE

    Human Follistatin-like 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Bioactivity-ELISA

     Follistatin-like 1 ELISA

    Immobilized Human BMP-4 Protein, premium grade (Cat. No. BM4-H5317) at 5 μg/mL (100 μL/well) can bind Human Follistatin-like 1, His Tag (Cat. No. FS1-H5227) with a linear range of 0.156-5 μg/mL (QC tested).

    Protocol

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Background

Follistatin-related protein 1 (FSTL1) is also known as Follistatin-like protein 1 (FRP). FSTL1 is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain and one VWFC domain. FSTL1 is overexpressed in synovial tissues from rheumatoid arthritis. Follistatin-like protein 1 / FSTL1 may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 binds heparin.

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