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Your Position: Home > Antibody > A17L > A1L-M698

Monoclonal Anti-Monkeypox virus (strain Zaire-96-I-16) A17L Antibody, Human IgG1 (1B4)

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  • Source
    Monoclonal Anti-Monkeypox virus (strain Zaire-96-I-16) A17L Antibody, Human IgG1 (1B4) is a chimeric monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with A17L.
  • Isotype
    Human IgG1 | Human Kappa
  • Specificity
    This product is a specific antibody specifically reacts with A17L.
  • Application
    ELISA
  • Purity

    >90% as determined by SDS-PAGE.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20 to -70°C for 12 months in lyophilized state from date of receipt;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
A17L SDS-PAGE

Monoclonal Anti-Monkeypox virus (strain Zaire-96-I-16) A17L Antibody, Human IgG1 (1B4) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-Elisa
 A17L ELISA

Immobilized Monkeypox virus (strain Zaire-96-I-16) A17L Protein, His Tag (Cat. No. A1L-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox virus (strain Zaire-96-I-16) A17L Antibody, Human IgG1 (1B4) (Cat. No. A1L-M698) with a linear range of 0.06-2 ng/mL (QC tested).

Bioactivity-SPR
 A17L SPR

Monoclonal Anti-Monkeypox virus (strain Zaire-96-I-16) A17L Antibody, Human IgG1 (1B4) (Cat. No. A1L-M698) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) A17L Protein, His Tag (Cat. No. A1L-M52H3) with an affinity constant of 7.98 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. The envelope glycoprotein A35R on the EV surface has been predicted to influence intercellular diffusion of virions.
  • Clinical and Translational Updates

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ETA of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2310.00

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