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ALPP

ALPP

ALPP Overview

Molecule Name
Alkaline phosphatase, placental type
Synonyms
PLAP
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
Alkaline phosphatase Regan isozyme，Placental alkaline phosphatase 1，PLAP-1
Background
ALPP is highly expressed in a variety of solid tumors, including ovarian, endometrial, germ cell, non-small cell lung, bladder and gastric cancers.In normal tissues, it is expressed in the placenta and low in lung and reproductive tissues.ALPP is a membrane protein and exits as a homodimer.

ALPP Product List

Species
  • Human（2）
  • Cynomolgus（1）
  • Rat（1）
Tag
  • His Tag（3）
  • His Tag & Avi Tag（1）
Host
  • HEK293（4）
Conjugate
  • Unconjugated（3）
  • Biotin-labeled（1）
Grade
  • RUO（4）
Low Endotoxin
  • No（4）
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
ALPP
HOTAvitag
ALP-H82E3
Biotinylated Human ALPP Protein, His,Avitag™ (active enzyme, MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISAEnzyme

$350.00

25ug
ALPP
HOT
ALP-H52H3
Human ALPP Protein, His Tag (active enzyme, Mass Spec & MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISAEnzyme

$390.00

100ug
ALPP
HOT
ALP-R52H4
Rat ALPP Protein, His Tag (active enzyme)
Rat
HEK293
SDS-PAGE
ELISAEnzyme

$390.00

100ug
ALPP
ALP-C52H3
Cynomolgus ALPP Protein, His Tag (active enzyme)
Cynomolgus
HEK293
SDS-PAGE
ELISAEnzyme

$390.00

100ug
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Resources

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Retroviral vector-transduced autologous T cells to express anti-ALPP CARs (TCRCure Biopharma Corporation)Phase 2 ClinicalXinqiao Hospital, Army Medical University
Endometrial Neoplasms; Ovarian Neoplasms; Solid tumours
Details
anti-ALPP CAR T-cell therapy (TCRCure Biopharma)TC-A101Phase 1 ClinicalTcrcure Biopharma Ltd
Solid tumours
Details
Customer Reviews