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Amphiregulin

Amphiregulin Overview

English NameAmphiregulinApproved Drugs0
Drugs in Clinical Trials2Target SynonymAREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Highest Development StagePhase 1 Clinical
English NameAmphiregulin
Target SynonymAREGB，Colorectum cell-derived growth factor，AR，Schwannoma-Derived Growth Factor，Amphiregulin B，CRDGF，SDGF，SDGF GN
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 1 Clinical

Amphiregulin Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    His Tag & Avi Tag (2)

  • Conjugate

    Biotin-labeled (2)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
AMN-H82Q3
Human
HEK293
Biotinylated Human Amphiregulin Protein, His,Avitag™
AMN-H82Q4
Human
HEK293
Biotinylated Human Amphiregulin Protein, His,Avitag™ (HPLC verified)
Total: 2
  • 1
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Amphiregulin Background

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

Amphiregulin Synonyms

AR, AREGB, CRDGF, SDGF

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
SRN-001SRN-001Phase 1 ClinicalsiRNAgen Therapeutics IncMetabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Chronic Kidney Disease-Mineral and Bone Disorder
Details
PMG-1015PMG-1015Phase 1 ClinicalPulmongene LtdIdiopathic Pulmonary Fibrosis
Details
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  • Clinical Drug Information
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