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Angiogenin

Angiogenin Overview

English NameAngiogeninApproved Drugs0
Drugs in Clinical Trials0Target SynonymRibonuclease 5，RNASE5，RAA1，Homo Sapiens Epididymis Luminal Protein 168，Angiogenin， Ribonuclease， RNase A Family， 5，Ribonuclease A Family Member 5，RNase 5，HEL168，Epididymis Luminal Protein 168
Highest Development StagePreclinical
English NameAngiogenin
Target SynonymRibonuclease 5，RNASE5，RAA1，Homo Sapiens Epididymis Luminal Protein 168，Angiogenin， Ribonuclease， RNase A Family， 5，Ribonuclease A Family Member 5，RNase 5，HEL168，Epididymis Luminal Protein 168
Approved Drugs0
Drugs in Clinical Trials0
Highest Development StagePreclinical

Angiogenin Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeatureOrder Now
ANN-H5149
Human
E. coli
Human Angiogenin / RNASE5 Protein, His Tag (SPR verified)
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Total: 1
  • 1

Angiogenin Background

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo

Angiogenin Synonyms

ALS9,ANG,Angiogenin,angiogenin, ribonuclease, RNase A family, 5,EC 3.1.27,EC:3.1.27.-
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