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Axl

Axl Overview

English NameAXL receptor tyrosine kinaseApproved Drugs2
Drugs in Clinical Trials30Target SynonymEC:2.7.10.1，EC 2.7.10，UFO，AXL Transforming Sequence/Gene，AXL Oncogene，EC 2.7.10.1，JTK11，Tyro7，ARK，Tyrosine-protein kinase receptor UFO，AXL，AXL Receptor Tyrosine Kinase
Highest Development StageApproved
English NameAXL receptor tyrosine kinase
Target SynonymEC:2.7.10.1，EC 2.7.10，UFO，AXL Transforming Sequence/Gene，AXL Oncogene，EC 2.7.10.1，JTK11，Tyro7，ARK，Tyrosine-protein kinase receptor UFO，AXL，AXL Receptor Tyrosine Kinase
Approved Drugs2
Drugs in Clinical Trials30
Highest Development StageApproved

Axl Product List

  • Product Category

    Protein (4)

  • Product Status

    Launched (5)

  • Species

    Human (3)Cynomolgus (1)

  • Tag

    His Tag (2)Fc Tag (1)Fc Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (3)Biotin-labeled (1)

Total: 4
  • 1

Axl Background

AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.

Axl Synonyms

AXL,UFO

Project Cooperation

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