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BMPR-1A

BMPR-1A Overview

English NameBone morphogenetic protein receptor type-1AApproved Drugs2
Drugs in Clinical Trials2Target SynonymBone Morphogenetic Protein Receptor Type 1A，EC 2.7.11，Activin receptor-like kinase 3，Bone morphogenetic protein receptor type-1A，ALK3，BMPR1A，Bone Morphogenetic Protein Receptor， Type IA，Serine/Threonine-Protein Kinase Receptor R5，ACVRLK3，BMPR-1A，SKR5，Activin A Receptor， Type II-Like Kinase 3，CD292 Antigen，EC 2.7.11.30，10q23del，CD292，BMP type-1A receptor，ALK-3，EC:2.7.11.30
Highest Development StageApproved
English NameBone morphogenetic protein receptor type-1A
Target SynonymBone Morphogenetic Protein Receptor Type 1A，EC 2.7.11，Activin receptor-like kinase 3，Bone morphogenetic protein receptor type-1A，ALK3，BMPR1A，Bone Morphogenetic Protein Receptor， Type IA，Serine/Threonine-Protein Kinase Receptor R5，ACVRLK3，BMPR-1A，SKR5，Activin A Receptor， Type II-Like Kinase 3，CD292 Antigen，EC 2.7.11.30，10q23del，CD292，BMP type-1A receptor，ALK-3，EC:2.7.11.30
Approved Drugs2
Drugs in Clinical Trials2
Highest Development StageApproved

BMPR-1A Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    Fc Tag (1)His Tag (1)

  • Conjugate

    Unconjugated (2)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
AL3-H5259
Human
HEK293
Human BMPR-1A / ALK-3 Protein, Fc Tag
AL3-H52H9
Human
HEK293
Human BMPR-1A / ALK-3 Protein, His Tag (MALS verified)
Total: 2
  • 1

BMPR-1A Background

The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.

BMPR-1A Synonyms

BMPR-1A,ALK-3,ACVRLK3,CD292,SKR5

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Recombinant Human Bone Morphogenetic Protein-2（University Of Baghdad）Phase 1 ClinicalUniversity Of BaghdadDiabetes Mellitus; Hematologic Diseases; Hypertension
Details
Recombinant human bone morphogenetic protein 4 (Stemgen)HS-214; hrBMP4Phase 1 ClinicalStemgenAsthma; Bronchiolitis Obliterans; Glioblastoma; Lung Diseases; Rejection of lung transplantation
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
Dibotermin alfaYM-484; rhBMP-2/CPMApprovedMedtronicInductosEUTibial FracturesMedtronic Biopharma Bv2002-09-09Fractures, Bone; Osteoarthritis; Osteoarthritis, Spine; Radius Fractures; Tibial Fractures; Tooth Injuries
Details
DWP-431DWP-431; rhBMP-2ApprovedDaewoong Pharmaceutical Co LtdNovosis, Novosis-DentalSouth KoreaAlveolar Bone LossDaewoong Pharmaceutical Co Ltd2013-01-01Alveolar Bone Loss; Intervertebral Disc Degeneration
Details
  • Overview
  • Product List
  • Marketed Drug Information
  • Clinical Drug Information
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