BMPR-1A

BMPR-1A

BMPR-1A Overview

Molecule Name
Bone morphogenetic protein receptor type-1A
Synonyms
BMPR-1A,ALK-3,ACVRLK3,CD292,SKR5
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs2
Highest Development StageApproved
Target Synonym
Bone Morphogenetic Protein Receptor Type 1A,EC 2.7.11,Activin receptor-like kinase 3,Bone morphogenetic protein receptor type-1A,ALK3,BMPR1A,Bone Morphogenetic Protein Receptor, Type IA,Serine/Threonine-Protein Kinase Receptor R5,ACVRLK3,BMPR-1A,SKR5,Activin A Receptor, Type II-Like Kinase 3,CD292 Antigen,EC 2.7.11.30,10q23del,CD292,BMP type-1A receptor,ALK-3,EC:2.7.11.30
Background
The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.

BMPR-1A Product List

Species
  • Human(2)
Tag
  • Fc Tag(1)
  • His Tag(1)
Host
  • HEK293(2)
Conjugate
  • Unconjugated(2)
Grade
  • RUO(2)
Low Endotoxin
  • No(2)
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
BMPR-1A
Human BMPR-1A / ALK-3 Protein, Fc Tag
Human
HEK293
SDS-PAGE

$245.00

200ug
BMPR-1A
Human BMPR-1A / ALK-3 Protein, His Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE

$270.00

200ug
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Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Recombinant Human Bone Morphogenetic Protein-2(University Of Baghdad)Phase 1 ClinicalUniversity Of Baghdad
Diabetes Mellitus; Hematologic Diseases; Hypertension
Details
Recombinant human bone morphogenetic protein 4 (Stemgen)HS-214; hrBMP4Phase 1 ClinicalStemgen
Asthma; Bronchiolitis Obliterans; Glioblastoma; Lung Diseases; Rejection of lung transplantation
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyFirst Brand NameFirst Approved CountryFirst IndicationFirst Approved CompanyFirst Approved DateIndicationClinical Trial
Dibotermin alfaYM-484; rhBMP-2/CPMApprovedMedtronicInductosEUTibial FracturesMedtronic Biopharma Bv2002-09-09
Fractures, Bone; Osteoarthritis; Osteoarthritis, Spine; Radius Fractures; Tibial Fractures; Tooth Injuries
Details
DWP-431DWP-431; rhBMP-2ApprovedDaewoong Pharmaceutical Co LtdNovosis, Novosis-DentalSouth KoreaAlveolar Bone LossDaewoong Pharmaceutical Co Ltd2013-01-01
Alveolar Bone Loss; Intervertebral Disc Degeneration
Details
Customer Reviews