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Home PageAll MoleculesCadherin-3
Cadherin-3
Cadherin-3 Overview
| English Name | Cadherin 3 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 7 | Target Synonym | Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Cadherin 3 |
| Target Synonym | Cadherin 3， Type 1， P-Cadherin (Placental)，Placental Cadherin，CDHP，P-cadherin，CDH3，Cadherin 3，Calcium-Dependent Adhesion Protein， Placental，Cadherin 3， P-Cadherin (Placental)，Cadherin-3，HJMD，PCAD |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 7 |
| Highest Development Stage | Phase 2 Clinical |
Cadherin-3 Product List
- Product Category
Protein (3)
- Product Status
Launched (3)
- Species
Human (1)Mouse (1)Cynomolgus (1)
- Tag
His Tag (3)
- Conjugate
Unconjugated (3)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human Cadherin-3 Protein, His Tag, low endotoxin |  |  |  |  Add to Cart | |
 Mouse | HEK293 | Mouse Cadherin-3 Protein, His Tag |  | | Add to Cart | ||
 Cynomolgus | HEK293 | Cynomolgus Cadherin-3 Protein, His Tag |  | | Add to Cart |
Total: 3
- 1
Cadherin-3 Background
Cadherin-3 (CDH3), also known as P-Cadherin, is a classical cadherin that functions as a calcium-dependent glycoprotein mediating cell-cell adhesion. Structurally, it is characterized by five extracellular cadherin repeats, a single transmembrane domain, and a highly conserved cytoplasmic tail. The CDH3 gene resides within a cadherin cluster on chromosome 16q, a genomic region linked to loss of heterozygosity in breast and prostate cancer. Furthermore, aberrant expression of the protein is implicated in the pathology of cervical adenocarcinoma.
Cadherin-3 Synonyms
CDH3,CDHP,Cadherin-3,P-cadherin
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| STEMVAC | EP-101 | Phase 2 Clinical | Epithany | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; HR-positive breast cancer; Lung Neoplasms; Triple Negative Breast Neoplasms | Details |
| BC-3195 | BC3195; BC-3195 | Phase 2 Clinical | Wuxi BioCity | Neoplasm Metastasis; Neoplasms; Solid tumours | Details |
| FF-21101-Y-90 | FF-21101-Y-90; PPMX-T002 | Phase 1 Clinical | Fujifilm Holdings Corp | Solid tumours | Details |
| FF-21101 | FF-21101 | Phase 1 Clinical | Perseus Proteomics Inc | Bile Duct Neoplasms; Colorectal Neoplasms; Head and Neck Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours | Details |
| TRAILR2/CDH3 bispecific antibody (Boehringer Ingelheim) | Phase 1 Clinical | Boehringer Ingelheim International Gmbh | Neoplasms | Details | |
| AMG 305 | AMG 305; AMG-305 | Phase 1 Clinical | Amgen Inc | Solid tumours | Details |
| FF-21101In | FF-21101In | Phase 1 Clinical | PeptiDream Inc | Solid tumours | Details |
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