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CD23

CD23 Overview

English NameImmunoglobulin epsilon Fc receptorApproved Drugs0
Drugs in Clinical Trials2Target SynonymLow affinity immunoglobulin epsilon Fc receptor，FCE2，CD23A，FCER2，CLEC4J，BLAST-2，Fc Fragment Of IgE Receptor II，C-Type Lectin Domain Family 4， Member J，Immunoglobulin Epsilon-Chain，CD23，Lymphocyte IgE Receptor，Fc Epsilon Receptor II，Fc-Epsilon-RII，CD23 Antigen，IGEBF，Fc Fragment Of IgE， Low Affinity II， Receptor For (CD23A)，C-Type Lectin Domain Family 4 Member J，Immunoglobulin E-binding factor，Fc Fragment Of IgE， Low Affinity II， Receptor For (CD23)
Highest Development StagePhase 2 Clinical
English NameImmunoglobulin epsilon Fc receptor
Target SynonymLow affinity immunoglobulin epsilon Fc receptor，FCE2，CD23A，FCER2，CLEC4J，BLAST-2，Fc Fragment Of IgE Receptor II，C-Type Lectin Domain Family 4， Member J，Immunoglobulin Epsilon-Chain，CD23，Lymphocyte IgE Receptor，Fc Epsilon Receptor II，Fc-Epsilon-RII，CD23 Antigen，IGEBF，Fc Fragment Of IgE， Low Affinity II， Receptor For (CD23A)，C-Type Lectin Domain Family 4 Member J，Immunoglobulin E-binding factor，Fc Fragment Of IgE， Low Affinity II， Receptor For (CD23)
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 2 Clinical

CD23 Product List

  • Product Category

    Protein (3)

  • Product Status

    Launched (3)

  • Species

    Human (2)Mouse (1)

  • Tag

    His Tag & Avi Tag (1)His Tag (2)

  • Conjugate

    Biotin-labeled (1)Unconjugated (2)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
CD3-H5249
Human
HEK293
Human CD23 / Fc epsilon RII Protein, His Tag (MALS verified)
CD3-H82Q5
Human
HEK293
Biotinylated Human CD23 / Fc epsilon RII Protein, His,Avitag™ (MALS & SPR verified)
CD3-M5243
Mouse
HEK293
Mouse CD23 / Fc epsilon RII Protein, His Tag (MALS verified)
Total: 3
  • 1

CD23 Background

Cluster of differentiation 23 (CD23) is also known as Low affinity immunoglobulin epsilon Fc receptor (FCER2), C-type lectin domain family 4 member J (CLEC4J), Fc-epsilon-RII (FcεRII), Immunoglobulin E-binding factor (IGEBF), is the 'low-affinity' receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets.

CD23 Synonyms

FCER2,CD23,CD23A,CLEC4J,FCE2,IGEBF,FcεRII,FcεRⅡ

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
UB-221UB-221Phase 2 ClinicalChinese Academy Of SciencesChronic Urticaria
Details
RO-7297089RO-7297089; AFM-26; RG-6296Phase 1 ClinicalGenentech IncMultiple Myeloma
Details
  • Overview
  • Product List
  • Clinical Drug Information
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