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Home PageAll MoleculesCD6
CD6
CD6 Overview
| English Name | T-cell differentiation antigen CD6 | Approved Drugs | 1 |
| Drugs in Clinical Trials | 1 | Target Synonym | T12，CD6，CD6 Molecule，TP120，T-Cell Differentiation Antigen CD6，CD6 Antigen |
| Highest Development Stage | Approved | ||
| English Name | T-cell differentiation antigen CD6 |
| Target Synonym | T12，CD6，CD6 Molecule，TP120，T-Cell Differentiation Antigen CD6，CD6 Antigen |
| Approved Drugs | 1 |
| Drugs in Clinical Trials | 1 |
| Highest Development Stage | Approved |
CD6 Product List
- Product Category
Protein (6)
- Product Status
Launched (6)
- Species
Human (3)Cynomolgus (3)
- Tag
His Tag (2)His Tag & Avi Tag (2)Fc Tag & Avi Tag (2)
- Conjugate
Unconjugated (2)Biotin-labeled (4)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
HOT CD6-H52H7 |  Human | HEK293 | Human CD6 / TP120 Protein, His Tag |  |  | |
HOT CD6-H82E3 | Human | HEK293 | Biotinylated Human CD6 Protein, His,Avitag™ (MALS verified) |  | |  |
CD6-H82F3 | Human | HEK293 | Biotinylated Human CD6 / TP120 Protein, Fc,Avitag™ (MALS verified) |  | | |
CD6-C52H3 |  Cynomolgus | HEK293 | Cynomolgus CD6 Protein, His Tag (MALS verified) |  | | |
CD6-C82E3 | Cynomolgus | HEK293 | Biotinylated Cynomolgus CD6 Protein, His,Avitag™ (MALS verified) |  | | |
CD6-C82F3 | Cynomolgus | HEK293 | Biotinylated Cynomolgus CD6 / TP120 Protein, Fc,Avitag™ (MALS verified) |  | | |
Total: 6
- 1
CD6 Background
CD6 (Cluster of Differentiation 6) is a cell surface glycoprotein that is involved in T cell activation and a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. The majority of peripheral blood T cells, a subset of B cells, and a subset of neuronal cells express CD6. CD6 appears to play a role as both a costimulatory molecule in T cell activation and as an adhesion receptor. Studies demonstrating a mitogenic effect for T cells with some CD6 specific monoclonal antibodies, in conjunction with either accessory cells or PMA and anti-CD2 mAb, support the concept of CD6 as a co stimulatory molecule.
CD6 Synonyms
CD6,TP120,T12
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells therapy (City of Hope Medical Center) | Phase 1 Clinical | City Of Hope National Medical Center | Diabetes Mellitus, Type 1; Graft vs Host Disease; Hemic and Lymphatic Diseases | Details |
Marketed Drug Information
| English Name | Research Code | Highest Development Stage | Company | Earliest Brand Name | Earliest Approval Country | Earliest Indication | Earliest Approval Company | Earliest Approval Date | Indication | Clinical Trial |
|---|---|---|---|---|---|---|---|---|---|---|
| Itolizumab | T-1-hT; EQ-001; T-1-h; h-T1; Bmab-600; Bmab600 | Approved | Center Of Molecular Immunology | Alzumab | India | Plaque psoriasis | Biocon Ltd | 2013-01-01 | Asthma; Coronavirus Disease 2019 (COVID-19); Dermatomyositis; Graft vs Host Disease; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Plaque psoriasis; Psoriasis; Respiratory Distress Syndrome, Adult | Details |
Product Reviews
g***t2025-11-28
0People LikeWe use Human CD16 from AcroBiosystems since many years now for in vitro characterization of antibodies and we are very happy to have well documented certificate to set up our experiments.
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