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CEACAM-8

CEACAM-8 Overview

English NameNon specific cross-reacting antigen 95Approved Drugs1
Drugs in Clinical Trials1Target SynonymNon-specific cross-reacting antigen NCA-95，CGM6，Carcinoembryonic Antigen Gene Family Member 6，CD66b Antigen，NCA-95，CD67，Carcinoembryonic antigen CGM6，CD66b，CEACAM8，Carcinoembryonic Antigen Related Cell Adhesion Molecule 8，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8，CD67 Antigen，CEA Cell Adhesion Molecule 8
Highest Development StageApproved
English NameNon specific cross-reacting antigen 95
Target SynonymNon-specific cross-reacting antigen NCA-95，CGM6，Carcinoembryonic Antigen Gene Family Member 6，CD66b Antigen，NCA-95，CD67，Carcinoembryonic antigen CGM6，CD66b，CEACAM8，Carcinoembryonic Antigen Related Cell Adhesion Molecule 8，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8，CD67 Antigen，CEA Cell Adhesion Molecule 8
Approved Drugs1
Drugs in Clinical Trials1
Highest Development StageApproved

CEACAM-8 Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    His Tag (1)His Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (1)Biotin-labeled (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeatureOrder Now
CE8-H5224
Human
HEK293
Human CEACAM-8 / CD66b Protein, His Tag, low endotoxin (MALS verified)
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CE8-H82E9
Human
HEK293
Biotinylated Human CEACAM-8 / CD66b Protein, His,Avitag™ (SPR verified)
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Total: 2
  • 1

CEACAM-8 Background

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.

CEACAM-8 Synonyms

CEACAM8,CD66b,CD67,CGM6,NCA-95

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
90Y-DTPA-besilesomabTLX-66Phase 2 ClinicalTelix Pharmaceuticals LtdMultiple Myeloma; Neoplasms, Plasma Cell; Plasmacytoma
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
Besilesomab99Tcm-BW250-183; TLX-66-CDx; TLX66-CDx; BW-250-183ApprovedCis Bio International SaScintimunEUOsteomyelitisCis Bio International Sa2010-01-11Osteomyelitis
Details
  • Overview
  • Product List
  • Marketed Drug Information
  • Clinical Drug Information
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