CLEC5A
CLEC5A Product List
- Product Category
Protein (4)
- Product Status
Launched (4)
- Species
Human (2)Mouse (1)Cynomolgus / Rhesus macaque (1)
- Tag
His Tag (3)Fc Tag (1)
- Conjugate
Unconjugated (4)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature | Order Now |
|---|---|---|---|---|---|---|---|
 Human | HEK293 | Human CLEC5A / MDL-1 Protein, His Tag, active dimer, low endotoxin (MALS & SPR verified) |  |  |  Add to Cart | ||
| Human | HEK293 | Human CLEC5A / MDL-1 Protein, Fc Tag, low Endotoxin (MALS & SPR verified) |  | | | Add to Cart | |
 Mouse | HEK293 | Mouse CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified) |  | | | Add to Cart | |
 Cynomolgus / Rhesus macaque | HEK293 | Cynomolgus / Rhesus macaque CLEC5A / MDL-1 Protein, His Tag, low endotoxin (MALS & SPR verified) | | | Add to Cart |
Total: 4
- 1
CLEC5A Background
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
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