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DLL1

DLL1 Overview

English NameDelta Like Canonical Notch Ligand 1Approved Drugs0
Drugs in Clinical Trials0Target SynonymDelta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Highest Development StagePreclinical
English NameDelta Like Canonical Notch Ligand 1
Target SynonymDelta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
Approved Drugs0
Drugs in Clinical Trials0
Highest Development StagePreclinical

DLL1 Product List

  • Product Category

    Protein (3)Cell Grade Beads (2)

  • Product Status

    Launched (5)

  • Species

    Human (3)- (2)

  • Tag

    His Tag (1)His Tag & Avi Tag (1)- (2)Fc Tag (1)

  • Conjugate

    Unconjugated (2)Biotin-labeled (1)- (2)

Total: 5
  • 1

DLL1 Background

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

DLL1 Synonyms

DLL1,Delta1,H-Delta-1
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