EREG Overview
Molecule Name
Epiregulin
Synonyms
EPR, ER, Ep
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
Epiregulin，Ep，EREG，EPR，ER，Proepiregulin
Background
EREG is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4), which stimulates tyrosine phosphorylation of EGFR and ERBB4. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, EREG may promote the progression of cancers of various human tissue.
EREG Product List
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Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Fepixnebart | LY-3016859 | Phase 2 Clinical | Eli Lilly And Company | Diabetic Nephropathies; Diabetic Neuropathies; Low Back Pain; Osteoarthritis; Osteoarthritis, Knee | Details |
| Epiregulin Antibody | LY3848575; LY-3848575 | Phase 2 Clinical | Eli Lilly And Company | Neuralgia; Polyneuropathies | Details |