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FOLR1

FOLR1 Overview

English NameFolate receptor alphaApproved Drugs3
Drugs in Clinical Trials20Target SynonymFRalpha，KB cells FBP，Adult folate-binding protein，Folate receptor 1，Folate receptor alpha，FR-alpha，FOLR1，Ovarian Tumor-Associated Antigen MOv18，Folate Receptor 1 (Adult)，Folate Receptor， Adult，FOLR，FBP，Folate Binding Protein，FRα
Highest Development StageApproved
English NameFolate receptor alpha
Target SynonymFRalpha，KB cells FBP，Adult folate-binding protein，Folate receptor 1，Folate receptor alpha，FR-alpha，FOLR1，Ovarian Tumor-Associated Antigen MOv18，Folate Receptor 1 (Adult)，Folate Receptor， Adult，FOLR，FBP，Folate Binding Protein，FRα
Approved Drugs3
Drugs in Clinical Trials20
Highest Development StageApproved

FOLR1 Product List

  • Product Category

    Protein (16)Cell (1)Antibody (1)

  • Product Status

    Launched (20)

  • Species

    Mouse (3)Cynomolgus / Rhesus macaque (2)Human (12)Rabbit (1)

  • Tag

    His Tag (8)His Tag & Avi Tag (4)Fc Tag (3)Fc Tag & Avi Tag (1)- (4)

  • Conjugate

    Unconjugated (8)Biotin-labeled (5)FITC Labeled (1)PE Labeled (2)APC Labeled (1)- (3)

Total: 18
  • 1
  • 2

FOLR1 Background

Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.

FOLR1 Synonyms

FOLR-1,FBP,FOLR,FRα

Antibody Project Trading Platform

Project Cooperation

Product Reviews

  • p***g2025-01-23
    0People Like
    Human FOLR1 Protein, His Tag (Folic Acid Free, MALS verified)
    As expected, this was a high quality product. I have purchased multiple products from Acro to develop assays in the past. As usual, purity and quantity was confirmed by our in-house quality control group. We are using this in conjunction with #FO1-H82E2 Biotinylated Human FOLR1 Protein, His Avitag. The product was used successfully in an immunization campaign and will also be used for other in-house assays in the future.
  • D***m2022-10-26
    0People Like
    Human FOLR1 Protein, His Tag (Folic Acid Free, MALS verified)
    We had to order human folate receptor protein for 100 micrograms unit type for one of our sensitive studies. It was crucial that the product work as intended. We received the product in a timely manner, and the product work as intended for one of our studies. As an employee working at a lab, I thank you for all the scientists working hard to make great products!
  • D***n2022-10-26
    0People Like
    Human FOLR1 Protein, His Tag (Folic Acid Free, MALS verified)
    We had previously ordered this product and we made the mistake of ordering the smaller quantity needed. We contacted customer support letting them know that we needed to switch the order to the larger quantity. They were friendly and helpful when resolving this issue. After the switch, the item in question was sent out very quickly and we were able to continue with our study as soon as it arrived.
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