HLA-G & B2M & Peptide (RIIPRHLQL)

HLA-G & B2M & Peptide (RIIPRHLQL) Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    His Tag (1)His Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (1)Biotin-labeled (1)

HLA-G & B2M & Peptide (RIIPRHLQL) Background

Human leukocyte antigen-G (HLA-G) is a group of closely linked genes located on the short arm of human chromosome 6. Hla-g belongs to a non-classical major histocompatibility complex. MHC class I molecules are selectively highly expressed in extravvillous trophoblast cells invading the uterine decidual membrane.The gene structure of HLA-G is similar to that of HLA-A,HLA-B and HLA-C, but the termination code appears in advance so that the intracellular segment of protein product encoded by HLA-G is only 6 amino acids, which is significantly shorter than the 30 amino acids of classical HLA classI antigen. The Human HLA-G & B2M & RIIPRHLQL Complex Protein is a complex of HLA-G of the MHC Class I, B2M and RMFPNAPYL peptide.

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
OsugacestatAL-101(BMS); BMS-906024Phase 2 ClinicalBristol-Myers Squibb Company, Glaxosmithkline PlcTriple Negative Breast Neoplasms; Neoplasms; Carcinoma, Adenoid Cystic; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Details
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  • Clinical Drug Information
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