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Menu
Home PageAll MoleculesIRAK4
IRAK4
IRAK4 Product List
- Product Category
Protein (5)
- Product Status
Launched (5)
- Species
Human (2)Canine (1)Mouse (1)Cynomolgus (1)
- Tag
His Tag (4)GST Tag (1)
- Conjugate
Unconjugated (5)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
IR4-H5533 |  Human | InsectCells | Human IRAK4 Protein, GST Tag (active enzyme, HPLC verified) |  |  | |
IR4-H5546 | Human | InsectCells | Human IRAK4 Protein, His Tag |  | | |
IR4-M5544 |  Mouse | InsectCells | Mouse IRAK4 Protein, His Tag (active enzyme) |  | ||
IR4-C5545 |  Canine | InsectCells | Canine IRAK4 Protein, His Tag (active enzyme) |  | | |
IR4-C5546 |  Cynomolgus | InsectCells | Cynomolgus IRAK4 Protein, His Tag (active enzyme) |  | |
Total: 5
- 1
IRAK4 Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Fiztasovimab | NPC-21 | Phase 2 Clinical | Nobelpharma Co Ltd | Cytomegalovirus Infections | Details |
| TRL-345 | CMV-345; TRL-345 | Phase 1 Clinical | Trellis Bioscience LLC | Cytomegalovirus Infections | Details |
- Product List
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