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L1R (MPXV)

L1R (MPXV) Product List

  • Product Category

    Protein (2)Antibody (1)

  • Product Status

    Launched (3)

  • Species

    Monkeypox virus (strain Zaire-96-I-16) (1)Mouse (1)Monkeypox virus (Democratic Republic of the Congo) (1)

  • Tag

    His Tag (2)- (1)

  • Conjugate

    Unconjugated (3)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
L1R-M663
Mouse
HEK293
Monoclonal Anti-Monkeypox-L1R Antibody, Human IgG1 (10D8)
L1R-M5241
Monkeypox virus (strain Zaire-96-I-16)
HEK293
Monkeypox virus (strain Zaire-96-I-16) L1R Protein, His Tag (HPLC verified)
L1R-M5243
Monkeypox virus (Democratic Republic of the Congo)
HEK293
Monkeypox virus (Democratic Republic of the Congo) L1R Protein, His Tag (MALS verified)
Total: 3
  • 1

L1R (MPXV) Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. L1R is essential for virus assembly and release.

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
SifuvirtideFS-0101; SFTPhase 2 ClinicalTianjin Fusogen Pharmaceuticals IncHIV Infections; Acquired Immunodeficiency Syndrome
Details
LP-51LP-51Phase 2 ClinicalInstitute Of Pathogenic Biology Chinese Academy Of Medical SciencesHIV Infections; Sjogren's Syndrome
Details
PGT-121PGT-121Phase 2 ClinicalInternational Aids Vaccine Initiative, Theraclone Sciences Inc, The Scripps Research Institute Inc, The Ragon Institute Of Mgh, Mit And HarvardHIV Infections; Acquired Immunodeficiency Syndrome; Retroviridae Infections; Sexually Transmitted Diseases, Viral; HIV Seropositivity
Details
MPER-656 liposome vaccineMPER-656Phase 1 ClinicalNational Institute Of Allergy And Infectious Diseases (Niaid)HIV Infections
Details
Microbicide monoclonal antibody triple combination (Polymun Scientific Immunobiologische Forschung)Phase 1 ClinicalPolymun Scientific GmbhHIV Infections
Details
ElipovimabGS-9722Phase 1 ClinicalHIV Infections
Details
CPT-31CPT-31; CPT31-LAPhase 1 ClinicalNavigenPurpura, Thrombocytopenic, Idiopathic; HIV Infections
Details
FB-1002(Frontier Biotechnologies)FB-1002(前沿生物)Phase 1 ClinicalShanghai Institute Of Materia Medica, Chinese Academy Of SciencesCoronavirus Disease 2019 (COVID-19)
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
AlbuvirtideFB-006MApproved艾可宁Mainland ChinaHIV InfectionsFrontier Biotechnologies Inc2018-05-23Acquired Immunodeficiency Syndrome; HIV Infections
Details
EnfuvirtideT-20; R-698; DP-178ApprovedF. Hoffmann-La Roche LtdFuzeonUnited StatesHIV InfectionsF. Hoffmann-La Roche Ltd2003-03-13HIV Infections; Acquired Immunodeficiency Syndrome; HIV Seropositivity
Details
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