LIV-1

LIV-1

LIV-1 Overview

Molecule Name
Zinc transporter ZIP6
Synonyms
SLC39A6,LIV-1,ZIP6,Zinc transporter ZIP6,ZIP-6
Drug Development Progress
Drugs in Clinical Trials2
Approved Drugs0
Highest Development StagePhase 2 Clinical
Target Synonym
LIV-1,LIV1,LIV-1 Protein, Estrogen Regulated,Solute Carrier Family 39 (Metal Ion Transporter), Member 6,Zrt- and Irt-like protein 6,SLC39A6,Estrogen-regulated protein LIV-1,ZIP-6,Zinc transporter ZIP6,Solute Carrier Family 39 (Zinc Transporter), Member 6,Solute carrier family 39 member 6
Background
LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

LIV-1 Product List

Species
  • Human(7)
  • Cynomolgus(3)
  • Mouse(2)
  • Rat(1)
  • Rhesus macaque(1)
Tag
  • His Tag(6)
  • Fc Tag(4)
  • His Tag & Avi Tag(2)
  • -(1)
  • Fc Tag & Avi Tag(1)
Host
  • HEK293(14)
Conjugate
  • Unconjugated(11)
  • Biotin-labeled(3)
Grade
  • RUO(14)
Low Endotoxin
  • Yes(1)
  • No(13)
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&PriceAdd to Cart
LIV-1
HOTAvitag
LV1-H82E3
Biotinylated Human LIV-1 / SLC39A6 Protein, His,Avitag™
Human
HEK293
SDS-PAGE
ELISA

$470.00

25ug
LIV-1
Cynomolgus LIV-1 / SLC39A6 Protein, His Tag
Cynomolgus
HEK293
SDS-PAGE
ELISA

$535.00

100ug
LIV-1
Rat LIV-1 / SLC39A6 Protein, His Tag
Rat
HEK293
SDS-PAGE

$535.00

100ug
LIV-1
Human LIV-1 / SLC39A6 Protein, His Tag (Mass Spec verified)
Human
HEK293
SDS-PAGE
ELISASPR

$535.00

100ug
LIV-1
Cynomolgus LIV-1 / SLC39A6 Protein, His Tag
Cynomolgus
HEK293
SDS-PAGE
ELISA

$560.00

100ug
LIV-1
Avitag
LV1-C82E5
Biotinylated Cynomolgus LIV-1 / SLC39A6 Protein, His,Avitag™
Cynomolgus
HEK293
SDS-PAGE
ELISA

$380.00

25ug
LIV-1
Human LIV-1 / SLC39A6 Protein, Fc Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISASPR

$535.00

100ug
LIV-1
Human LIV-1 / SLC39A6 Protein, Fc Tag
Human
HEK293
SDS-PAGE
ELISA

$620.00

100ug
LIV-1
Human LIV-1 / SLC39A6 (229-325) Protein, Fc Tag (MALS verified)
Human
HEK293
MALSSDS-PAGE

$535.00

100ug
LIV-1
Human LIV-1 Full Length Protein (VLP)
Human
HEK293
ELISAIdentity

$620.00

20ug
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Asset Licensing Opportunity

Antibody Project Trading Platform

Project NameProject StageMolecule TypeMolecule SourceDisease AreaIndication
LIV-1 mAb - 01PCCMonoclonalHumanized MouseSolid TumorColorectal cancer,Breast cancer
Project Name
LIV-1 mAb - 01
Project Stage
PCC
Molecule Type
Monoclonal
Molecule Source
Humanized Mouse
Disease Area
Solid Tumor
Indication
Colorectal cancer,Breast cancer
Resources

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
Ladiratuzumab vedotinSGN-LIV1A; MK-6440; MK6440Phase 2 ClinicalMerck Sharp & Dohme Corp, Seagen Inc
Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Squamous Cell Carcinoma; Gastroesophageal Junction Neoplasms; Melanoma; Metastatic breast cancer; Prostatic Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms
Details
LaventatugBRY-812Phase 2 ClinicalZhejiang BioRay Biopharmaceuticals Co Ltd
Neoplasms; Solid tumours
Details
Customer Reviews
  • J***g2022-04-13
    When I was searching for this protein, there were not many options until I found ACRO. Very happy about various species as well as tag choices. ELISA results are reproducible and consistent. The delivery was fast whereas others may take longer. The product information is clear and comprehensive, which is very important for the research.