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LY75

LY75 Overview

English NameLymphocyte antigen 75Approved Drugs0
Drugs in Clinical Trials2Target SynonymLY75，CD205，Lymphocyte Antigen 75，C-Type Lectin Domain Family 13 Member B，CLEC13B，DEC-205，CD205 Antigen，Gp200-MR6，Ly-75
Highest Development StagePhase 2 Clinical
English NameLymphocyte antigen 75
Target SynonymLY75，CD205，Lymphocyte Antigen 75，C-Type Lectin Domain Family 13 Member B，CLEC13B，DEC-205，CD205 Antigen，Gp200-MR6，Ly-75
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 2 Clinical

LY75 Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Mouse (1)Human (1)

  • Tag

    His Tag (2)

  • Conjugate

    Unconjugated (2)

Total: 2
  • 1

LY75 Background

lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.

LY75 Synonyms

LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6
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