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Home PageAll MoleculesMICB
MICB
MICB Overview
| English Name | MHC class I polypeptide-related sequence B | Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 | Target Synonym | |
| Highest Development Stage | Phase 1 Clinical | ||
| English Name | MHC class I polypeptide-related sequence B |
| Target Synonym | |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 4 |
| Highest Development Stage | Phase 1 Clinical |
MICB Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Human (1)
- Tag
His Tag (1)
- Conjugate
Unconjugated (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
MIB-H52H3 |  Human | HEK293 | Human MICB Protein, His Tag (MALS verified) |  |  |  |
Total: 1
- 1
MICB Background
Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| Isuventatug | CLN-619 | Phase 1 Clinical | Cullinan MICA Corp | Carcinoma, Non-Small-Cell Lung; Multiple Myeloma; Solid tumours | Details |
| FT-536 | FT-536 | Phase 1 Clinical | Fate Therapeutics Inc | Abdominal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Ovarian Neoplasms; Solid tumours | Details |
| FT-836 | FT-836; FT836 | Phase 1 Clinical | Fate Therapeutics Inc | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Endometrial Neoplasms; Neoplasms; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck | Details |
| DM-919 | DM-919; DM919 | Phase 1 Clinical | D2M Biotherapeutics Inc | Neoplasms; Solid tumours | Details |
- Product List
- Clinical Drug Information
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