MIS RII

MIS RII

MIS RII Overview

Molecule Name
Anti-Mullerian hormone receptor II
Synonyms
MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor
Drug Development Progress
Drugs in Clinical Trials0
Approved Drugs0
Highest Development StagePreclinical
Target Synonym
Anti-Mullerian Hormone Receptor, Type II,AMHR2,MRII,AMH Type II Receptor,MISRII,Muellerian Inhibiting Substance Type II Receptor,MIS Type II Receptor,Anti-Muellerian hormone type-2 receptor,EC:2.7.11.30,Mullerian Inhibiting Substance Type II Receptor,MISR2,AMHR,Anti-Muellerian Hormone Type-2 Receptor,Anti-Mullerian Hormone Receptor Type 2,EC 2.7.11.30,Anti-Muellerian Hormone Type II Receptor,Anti-Mullerian Hormone Receptor Type II
Background
MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

MIS RII Product List

Species
  • Human(5)
  • Cynomolgus(1)
  • Mouse(1)
Tag
  • His Tag(3)
  • Fc Tag(1)
  • His Tag & Avi Tag(1)
  • Llama IgG Fc Tag(1)
  • Mouse IgG Fc Tag(1)
Host
  • HEK293(7)
Conjugate
  • Unconjugated(6)
  • Biotin-labeled(1)
Grade
  • RUO(7)
Low Endotoxin
  • Yes(1)
  • No(6)
MoleculeCat. No.Product NameSpeciesHostStructurePurityActivitySize&Price
MIS RII
Human MIS RII Protein, Fc Tag
Human
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Mouse MIS RII Protein, His Tag
Mouse
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Human MIS RII Protein, Mouse IgG2a Fc Tag
Human
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Human MIS RII Protein, His Tag
Human
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Cynomolgus MIS RII Protein, His Tag
Cynomolgus
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Human MIS RII Protein, Llama IgG2b Fc Tag, low endotoxin
Human
HEK293
SDS-PAGE

$360.00

100ug
MIS RII
Avitag
MII-H82E3
Biotinylated Human MIS RII Protein, His,Avitag™
Human
HEK293
SDS-PAGE

$360.00

25ug
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Customer Reviews
  • K***n2025-04-29
    We purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.