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Mucin-1

Mucin-1 Overview

English NameMucin-1Approved Drugs0
Drugs in Clinical Trials22Target SynonymPEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，KL-6，PEMT，EMA，Breast carcinoma-associated antigen DF3，Mucin 1， Transmembrane
Highest Development StagePhase 2 Clinical
English NameMucin-1
Target SynonymPEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，KL-6，PEMT，EMA，Breast carcinoma-associated antigen DF3，Mucin 1， Transmembrane
Approved Drugs0
Drugs in Clinical Trials22
Highest Development StagePhase 2 Clinical

Mucin-1 Product List

  • Product Category

    Protein (16)Antibody (1)Kits (1)

  • Product Status

    Launched (18)

  • Species

    Human (13)Cynomolgus (3)Mouse (2)

  • Tag

    Fc Tag (7)Llama IgG Fc Tag (1)His Tag (6)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)- (2)

  • Conjugate

    Unconjugated (15)Biotin-labeled (1)APC Labeled (1)- (1)

Total: 18
  • 1
  • 2

Mucin-1 Background

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Mucin-1 Synonyms

Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin
  • Overview
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