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Home PageAll MoleculesNkp46
Nkp46
Nkp46 Overview
| English Name | Natural cytotoxicity triggering receptor 1 | Approved Drugs | 0 |
| Drugs in Clinical Trials | 3 | Target Synonym | NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335 |
| Highest Development Stage | Phase 2 Clinical | ||
| English Name | Natural cytotoxicity triggering receptor 1 |
| Target Synonym | NK cell-activating receptor，NK-p46，Lymphocyte antigen 94 homolog，NKp46，hNKp46，Lymphocyte Antigen 94 Homolog (Activating NK-Receptor; NK-P46)，Natural killer cell p46-related protein，LY94，Lymphocyte Antigen 94 (Mouse) Homolog (Activating NK-Receptor; NK-P46)，CD335 Antigen，CD335 |
| Approved Drugs | 0 |
| Drugs in Clinical Trials | 3 |
| Highest Development Stage | Phase 2 Clinical |
Nkp46 Product List
- Product Category
Protein (16)Cell (2)Antibody (1)
- Product Status
Launched (19)
- Species
Human (12)Cynomolgus (3)Mouse (4)
- Tag
Fc Tag (4)His Tag (6)Llama IgG Fc Tag (2)Fc Tag & Avi Tag (1)His Tag & Avi Tag (3)- (2)Tag Free (1)
- Conjugate
Unconjugated (10)Biotin-labeled (5)- (2)PE Labeled (1)FITC Labeled (1)
Add to Cart
Total: 19
- 1
- 2
Nkp46 Background
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Nkp46 Synonyms
Nkp46
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| NY-303 | NY-303 | Phase 2 Clinical | NAYA Biosciences Inc | Carcinoma, Hepatocellular; Solid tumours | Details |
| IPH-6501 | IPH-6501; IPH-65 | Phase 2 Clinical | Innate Pharma SA | Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms | Details |
| SAR-443579 | SAR-443579; SAR443579; SAR'579; IPH6101; IPH-6101 | Phase 1 Clinical | Sanofi | Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematologic Diseases; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma | Details |
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