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OSMR

OSMR Overview

English NameOncostatin-M-specific receptor subunit betaApproved Drugs0
Drugs in Clinical Trials1Target SynonymIL-31R-beta，IL-31RB，Interleukin-31 receptor subunit beta，IL-31 receptor subunit beta，IL-31R subunit beta
Highest Development StagePhase 2 Clinical
English NameOncostatin-M-specific receptor subunit beta
Target SynonymIL-31R-beta，IL-31RB，Interleukin-31 receptor subunit beta，IL-31 receptor subunit beta，IL-31R subunit beta
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 2 Clinical

OSMR Product List

  • Product Category

    Protein (5)

  • Product Status

    Launched (5)

  • Species

    Cynomolgus (1)Human (3)Canine (1)

  • Tag

    His Tag (3)His Tag & Avi Tag (1)Fc Tag (1)

  • Conjugate

    Unconjugated (4)Biotin-labeled (1)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
HOT
OSR-C52H9
Cynomolgus
HEK293
Cynomolgus OSMR beta Protein, His Tag, low endotoxin (MALS verified)
OSR-H5253
Human
HEK293
Human OSMR beta Protein, Fc Tag, low endotoxin (MALS verified)
OSR-H52H9
Human
HEK293
Human OSMR beta Protein, His Tag, low endotoxin (MALS verified)
OSR-H82E3
Human
HEK293
Biotinylated Human OSMR beta Protein, His,Avitag™ (MALS verified)
OSR-C52H8
Canine
HEK293
Canis lupus OSMR beta Protein, His Tag (MALS verified)
Total: 5
  • 1

OSMR Background

Oncostatin-M-specific receptor subunit beta (OSMRβ), also known as Interleukin-31 receptor subunit beta (IL-31RB), is the beta subunit of the type II OSM receptor, which is a heterodimer of gp130 and OSMRβ. OSMRβ associates with the low-affinity OSM·gp130 complex to form a high-affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events.

OSMR Synonyms

Oncostatin-M-specific receptor subunit beta,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31R-beta,IL-31RB,OSMR,OSMRB

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
VixarelimabKPL-716; BIIB-069; RG-6536; RO-7622888Phase 2 ClinicalBiogen IncChronic Urticaria; Colitis, Ulcerative; Lichen Planus; Neurodermatitis; Plaque psoriasis; Prurigo Nodularis; Pruritus
Details
  • Overview
  • Product List
  • Clinical Drug Information
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