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Home PageAll MoleculesPAC1R
PAC1R
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PAC1R Background
PAC1R is a class B G-protein-coupled receptor primarily activated by the neuropeptide PACAP. Abundantly expressed in the nervous system, it acts as a critical pain modulator in the trigeminal vascular system, making it a premier therapeutic target for migraine, chronic pain, and stress-related disorders like PTSD.
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